Senescent CD8<sup>+</sup> T cells acquire NK cell-like innate functions to promote antitumor immunity.

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第一作者： Toshio,Kakuda

第一单位： Department of Urologye, Graduate School of Medicin, Ehime University, Toon, Japan.;Department of Immunology, Graduate School of Medicine, Ehime University, Toon, Japan.

作者： Toshio,Kakuda ^[1] ; Junpei,Suzuki ^[2] ; Yuko,Matsuoka ^[3] ; Tadahiko,Kikugawa ^[4] ; Takashi,Saika ^[4] ; Masakatsu,Yamashita ^[2]

作者单位： Department of Urologye, Graduate School of Medicin, Ehime University, Toon, Japan.;Department of Immunology, Graduate School of Medicine, Ehime University, Toon, Japan. ^[1] Department of Immunology, Graduate School of Medicine, Ehime University, Toon, Japan. ^[2] Translational Research Center, Ehime University Hospital, Ehime University, Toon, Japan. ^[3] Department of Urologye, Graduate School of Medicin, Ehime University, Toon, Japan. ^[4]

关键词 Menin T-cell innate functions antigen-independent cytotoxicity immunosenescence senescent CD8+ T cells

主题词小鼠(Mice);动物(Animals);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);杀伤细胞, 天然(Killer Cells, Natural);适应性免疫(Adaptive Immunity);黑色素瘤, 实验性(Melanoma, Experimental);衰老(Aging)

DOI 10.1111/cas.15824

PMID 37186472

发布时间 2023-07-18

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