Transcriptomic evidence for tumor-specific beneficial or adverse effects of TGFβ pathway inhibition on the prognosis of patients with liver cancer.

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第一作者： Matthis,Desoteux

第一单位： Inserm, UMR_S 1242, OSS (Oncogenesis Stress Signaling), Centre de Lutte contre le Cancer Eugène Marquis, Univ Rennes, France.

作者： Matthis,Desoteux ^[1] ; Betty,Maillot ^[2] ; Kevin,Bévant ^[1] ; Tanguy,Ferlier ^[1] ; Raffaële,Leroux ^[1] ; Gaëlle,Angenard ^[3] ; Corentin,Louis ^[1] ; Laurent,Sulpice ^[1] ; Karim,Boudjema ^[2] ; Cédric,Coulouarn ^[4]

作者单位： Inserm, UMR_S 1242, OSS (Oncogenesis Stress Signaling), Centre de Lutte contre le Cancer Eugène Marquis, Univ Rennes, France. ^[1] Department of Hepatobiliary and Digestive Surgery, Rennes University Hospital, France. ^[2] Inserm, Inrae, UMR_S 1317, NuMeCan (Nutrition, Metabolisms and Cancer), Univ Rennes, France. ^[3] Clinical Investigation Center 1414, CHU de Rennes, France. ^[4]

关键词 TGFβ galunisertib gene signature hepatocellular carcinoma survival

主题词人类(Humans);肝肿瘤(Liver Neoplasms);癌, 肝细胞(Carcinoma, Hepatocellular);转化生长因子β(Transforming Growth Factor beta);基因表达谱(Gene Expression Profiling)

DOI 10.1002/2211-5463.13647

PMID 37195148

发布时间 2023-07-05

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