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Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia.

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作者单位: Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney 2052, Australia. [1] Australian Centre for Nanomedicine, Faculty of Engineering, UNSW Sydney, Sydney 2052, Australia. [2] School of Clinical Medicine, Medicine and Health, UNSW Sydney, Sydney 2052, Australia. [3] Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia 4072, Australia. [4] Department of Haematology and Bone Marrow Transplant, St Vincent's Hospital Sydney, Sydney 2010, Australia. [5] St Vincent's Centre for Applied Medical Research (AMR), Sydney 2010, Australia. [6] St Vincent Clinical School, Faculty of Medicine and Health, UNSW Sydney, Sydney 2052, Australia. [7] Bioanalytical Mass Spectrometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney 2052, Australia. [8] School of Biomedical Sciences, Lowy Cancer Research Centre, UNSW Sydney, Sydney 2052, Australia. [9] Department of Haematology, Prince of Wales Hospital, Sydney 2031, Australia. [10] Leukaemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, Western Australia 6009, Australia. [11] Curtin Medical School, Curtin University, Perth, Western Australia 6102, Australia. [12] Department of Clinical Haematology, Oncology, Blood and Marrow Transplantation, Perth Children's Hospital, Perth, Western Australia 6009, Australia. [13] School of Medicine, University of Western Australia, Perth, Western Australia 6009, Australia. [14] University of New South Wales Centre for Childhood Cancer Research, UNSW Sydney, Sydney 2052, Australia. [15] Centre for Advanced Imaging, ARC Training Centre for Innovation in Biomedical Imaging Technologies, University of Queensland, St Lucia 4072, Australia. [16]
DOI 10.1126/scitranslmed.abm1262
PMID 37196067
发布时间 2024-01-17
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