The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis.

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作者： Younis,Hazari ; Hery,Urra ; Valeria A,Garcia Lopez ; Javier,Diaz ; Giovanni,Tamburini ; Mateus,Milani ; Philippe,Pihan ; Sylvere,Durand ; Fanny,Aprahamia ; Reese,Baxter ; Menghao,Huang ; X Charlie,Dong ; Helena,Vihinen ; Ana,Batista-Gonzalez ; Patricio,Godoy ; Alfredo,Criollo ; Vlad,Ratziu ; Fabienne,Foufelle ; Jan G,Hengstler ; Eija,Jokitalo ; Beatrice,Bailly-Maitre ; Jessica L,Maiers ; Lars,Plate ; Guido,Kroemer ; Claudio,Hetz

DOI 10.1101/2023.05.02.538835

PMID 37205565

发布时间 2023-05-21

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The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis.

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The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis.

bioRxiv

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