Estimating prognostic relevant cutoff values for a multiplex PCR detecting BCR::ABL1 in chronic myeloid leukemia patients on tyrosine kinase inhibitor therapy in resource-limited settings.

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作者： Saifu,Hailu ^[1] ; Samuel,Kinde ^[2] ; Michael,Cross ^[3] ; Aster,Tsegaye ^[4] ; Tsehayneh,Kelemu ^[5] ; Daniel,Seifu ^[6] ; Dawit,Alemayehu ^[1] ; Azeb,Tarekegn ^[1] ; Gutema,Jabessa ^[1] ; Desalegn,Abeje ^[7] ; Markos,Abebe ^[7] ; Abdulaziz,Sherif ^[7] ; Fisihatsion,Tadesse ^[7] ; Uwe,Platzbecker ^[7] ; Rawleigh,Howe ^[1] ; Amha,Gebremedhin ^[1]

作者单位： College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia. ^[1] Madda Walabu University, Bale Robe, Ethiopia. ^[2] College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia. Samuel.KindeBirru@medizin.uni-leipzig.de. ^[3] Leipzig University Hospital, Leipzig, Germany. Samuel.KindeBirru@medizin.uni-leipzig.de. ^[4] Armauer Hansen Research Institute, Addis Ababa, Ethiopia. Samuel.KindeBirru@medizin.uni-leipzig.de. ^[5] Leipzig University Hospital, Leipzig, Germany. ^[6] Armauer Hansen Research Institute, Addis Ababa, Ethiopia. ^[7]

关键词 BCR::ABL1 fusion gene Chronic myeloid leukemia (CML)Clinical lab performance Low- and middle-income countries (LMICs)Multiplex PCR Prognostic relevant cutoff values

主题词人类(Humans);预后(Prognosis);融合蛋白质类, bcr-abl(Fusion Proteins, bcr-abl);白血病, 髓系, 慢性, BCR-ABL阳性(Leukemia, Myelogenous, Chronic, BCR-ABL Positive);蛋白激酶抑制剂(Protein Kinase Inhibitors)

DOI 10.1007/s00277-023-05254-x

PMID 37212909

发布时间 2023-12-13

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