Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors.

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作者： Mritunjay,Pandey ^[1] ; Jian-Hua,Zhang ^[1] ; Poorni R,Adikaram ^[1] ; Claire,Kittock ^[1] ; Nicole,Lue ^[1] ; Adam,Awe ^[1] ; Katherine,Degner ^[1] ; Nirmal,Jacob ^[1] ; Jenna,Staples ^[1] ; Rachel,Thomas ^[1] ; Allison B,Kohnen ^[1] ; Sundar,Ganesan ^[2] ; Juraj,Kabat ^[2] ; Ching-Kang,Chen ^[3] ; William F,Simonds ^[1]

作者单位： Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (NIH), Bethesda, Maryland, USA. ^[1] Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA. ^[2] Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. ^[3]

关键词 G protein–coupled receptors G proteins Neuroscience Pain

主题词动物(Animals);小鼠(Mice);受体, GABA-B(Receptors, GABA-B);GTP结合蛋白质β亚单位(GTP-Binding Protein beta Subunits);信号传导(Signal Transduction);疼痛(Pain);RGS蛋白质类(RGS Proteins)

DOI 10.1172/jci.insight.134685

PMID 37219953

发布时间 2024-07-15

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JCI insight

2023年8卷13期

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Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors.

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Specific regulation of mechanical nociception by Gβ5 involves GABA-B receptors.

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