Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3.

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作者： Caroline N,Smith ^[1] ; Kyle,Kihn ^[2] ; Zachary A,Williamson ^[3] ; K Martin,Chow ^[1] ; Louis B,Hersh ^[1] ; Konstantin V,Korotkov ^[1] ; Daniel,Deredge ^[1] ; Jessica S,Blackburn ^[3]

作者单位： Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America. ^[1] University of Kentucky Markey Cancer Center, Lexington, Kentucky, United States of America. ^[2] University of Maryland School of Pharmacy, Baltimore, Maryland, United States of America. ^[3]

主题词动物(Animals);小鼠(Mice);抗体(Antibodies);骆驼, 新大陆(Camelids, New World);疾病模型, 动物(Disease Models, Animal);肿瘤(Neoplasms)

DOI 10.1371/journal.pone.0285964

PMID 37220097

发布时间 2024-06-04

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