Cytotoxicity and exhaustion markers of chimeric antigen receptor T cells targeting BCMA in multiple myeloma cell lines between patients and healthy donors.

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作者： Somsak,Prasongtanakij ^[1] ; Sarinthip,Preedagasamzin ^[2] ; Bunyada,Jittorntrum ^[1] ; Usanarat,Anurathapan ^[2] ; Teeraya,Puavilai ^[3] ; Pimjai,Niparuck ^[3] ; Pichika,Chantrathammachart ^[3] ; Thanakrit,Piyajaroenkij ^[3] ; Kitipong,Uaesoontrachoon ^[4] ; Ryosuke,Uchibori ^[5] ; Keiya,Ozawa ^[5] ; Ken,Ohmine ^[5] ; Suradej,Hongeng ^[6]

作者单位： Research, Academics and Innovation Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. ^[1] Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. ^[2] Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. ^[3] Genepeutic Bio, Co. Ltd., Bangkok, Thailand. ^[4] Division of Immuno-Gene & Cell Therapy, Jichi Medical University, Tochigi-ken, Japan. ^[5] Department of Medicine, School of Medicine, Jichi Medical University, Tochigi-ken, Japan. ^[6]

关键词 BCMA CAR cytotoxicity exhaustion multiple myeloma

主题词人类(Humans);多发性骨髓瘤(Multiple Myeloma);B细胞成熟抗原(B-Cell Maturation Antigen);细胞系, 肿瘤(Cell Line, Tumor);白细胞, 单核(Leukocytes, Mononuclear);免疫疗法, 过继(Immunotherapy, Adoptive);T淋巴细胞(T-Lymphocytes)

DOI 10.1111/ejh.14007

PMID 37222081

发布时间 2024-01-17

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