Quercetin prevents the ferroptosis of OPCs by inhibiting the Id2/transferrin pathway.

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作者： Yeyang,Wang ^[1] ; Wenjun,Li ^[2] ; Mingsen,Wang ^[3] ; Hongdong,Chen ^[4] ; Yongsheng,Li ^[5] ; Wei,Wei ^[5] ; Xuhua,Liu ^[6] ; Yuelin,Wu ^[2] ; Sidong,Luo ^[2] ; Xinfang,Liu ^[2] ; Man,Xiong ^[7]

作者单位： Department of Spine, Orthopaedic Center, Guangdong Second Provincial General Hospital, Guangzhou, 510000, PR China; Orthopaedic Center, Zhaoqing Central People's Hospital, Zhaoqing, 526040, PR China. ^[1] Department of Spine, Orthopaedic Center, Guangdong Second Provincial General Hospital, Guangzhou, 510000, PR China. ^[2] Department of Orthopedic, Traditional Chinese Medicine Hospital of Puning City, Puning, 515343, PR China; Department of Orthopedic, Chaoshan Renyu Hospital of Jieyang, Jieyang, 515300, PR China. ^[3] Department of General Surgery, Guangdong Second Provincial General Hospital, Southern Medical University, Guangzhou, 510317, PR China. ^[4] Guangdong Cord Blood Bank, Guangzhou, 510663, PR China; Guangzhou Municipality Tianhe Nuoya Bio-engineering Co., Ltd, Guangzhou, 510663, PR China. ^[5] Department of Orthopaedic Trauma, The Third Affiliated Hospital of Southern Medical University, Guangzhou, 510000, PR China. ^[6] School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, 510000, PR China. Electronic address: xiongman@gzucm.edu.cn. ^[7]

关键词 Ferroptosis Id2 Oligodendrocyte progenitor cells Quercetin Spinal cord injury Transferrin

主题词人类(Humans);髓鞘(Myelin Sheath);槲皮素(Quercetin);脊髓损伤(Spinal Cord Injuries);转铁蛋白(Transferrin)

DOI 10.1016/j.cbi.2023.110556

PMID 37230155

发布时间 2023-06-21

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