Secreted endogenous macrosomes reduce Aβ burden and ameliorate Alzheimer's disease.

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作者： Cunli,Wang ^[1] ; Yiming,Yang ^[2] ; Xiaoyu,Zhang ^[1] ; Zhenqiang,Shi ^[2] ; Huiling,Gao ^[2] ; Manli,Zhong ^[3] ; Yonggang,Fan ^[3] ; Hongyan,Zhang ^[4] ; Bo,Liu ^[2] ; Guangyan,Qing ^[1]

作者单位： School of Biomedical Engineering, Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Lingshui Road, Dalian 116024, P. R. China. ^[1] Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, P. R. China. ^[2] College of Life and Health Sciences, Northeastern University, Shenyang 110819, P. R. China. ^[3] Health Sciences Institute, Key Laboratory of Major Chronic Diseases of Nervous System, China Medical University, Shenyang, 110122, P. R. China. ^[4] Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China. ^[5]

主题词小鼠(Mice);动物(Animals);阿尔茨海默病(Alzheimer Disease);蛋白质组学(Proteomics);淀粉样β肽类(Amyloid beta-Peptides);小神经胶质细胞(Microglia);疾病模型, 动物(Disease Models, Animal)

DOI 10.1126/sciadv.ade0293

PMID 37235655

发布时间 2023-06-15

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Science advances

2023年9卷21期

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Secreted endogenous macrosomes reduce Aβ burden and ameliorate Alzheimer's disease.

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Secreted endogenous macrosomes reduce Aβ burden and ameliorate Alzheimer's disease.

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