A study of targeted mutation of l-rhamnose isomerase to improve the conversion efficiency of D-allose.

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第一作者： Shuangshuang,Duan

第一单位： State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology (Shandong Academy of Science), Jinan 250353, PR China; Shandong Provincial Key Laboratory of Microbial Engineering, Department of Bioengineering, Qilu University of Technology (Shandong Academy of Science) Jinan 250353, PR China.

作者： Shuangshuang,Duan ^[1] ; Yonghua,Chen ^[1] ; Guodong,Wang ^[1] ; Zebin,Li ^[1] ; Shitong,Dong ^[1] ; Yingshuai,Wu ^[1] ; Yuanwei,Wang ^[1] ; Chunling,Ma ^[2] ; Ruiming,Wang ^[3]

作者单位： State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology (Shandong Academy of Science), Jinan 250353, PR China; Shandong Provincial Key Laboratory of Microbial Engineering, Department of Bioengineering, Qilu University of Technology (Shandong Academy of Science) Jinan 250353, PR China. ^[1] State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology (Shandong Academy of Science), Jinan 250353, PR China; Shandong Provincial Key Laboratory of Microbial Engineering, Department of Bioengineering, Qilu University of Technology (Shandong Academy of Science) Jinan 250353, PR China. Electronic address: machunling20022@163.com. ^[2] State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology (Shandong Academy of Science), Jinan 250353, PR China; Shandong Provincial Key Laboratory of Microbial Engineering, Department of Bioengineering, Qilu University of Technology (Shandong Academy of Science) Jinan 250353, PR China. Electronic address: ruiming3k@163.com. ^[3]

关键词 D-allose D-psicose Directed mutation L-rhamnose isomerase Semi-rational design

主题词葡萄糖(Glucose);果糖(Fructose);醛糖酮糖异构酶类(Aldose-Ketose Isomerases);突变(Mutation)

DOI 10.1016/j.enzmictec.2023.110259

PMID 37245327

发布时间 2023-06-12

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