Nano-particulate Toll-like Receptor 9 Agonist Potentiates the Antitumor Activity of Anti-Glypican-1 Antibody.

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第一作者： Yurina,Saito

第一单位： Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.

作者： Yurina,Saito ^[1] ; Tsuyoshi,Takahashi ^[2] ; Kosuke,Hiramatsu ^[3] ; Satoshi,Serada ^[2] ; Minoru,Fujimoto ^[4] ; Tomoharu,Ohkawara ^[2] ; Takahito,Sugase ^[5] ; Takahiko,Nishigaki ^[2] ; Koji,Tanaka ^[6] ; Yasuhiro,Miyazaki ^[2] ; Tomoki,Makino ^[6] ; Yukinori,Kurokawa ^[1] ; Kiyokazu,Nakajima ^[1] ; Makoto,Yamasaki ^[2] ; Ken J,Ishii ^[1] ; Hidetoshi,Eguchi ^[1] ; Yuichiro,Doki ^[1] ; Tetsuji,Naka ^[1]

作者单位： Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan. ^[1] Laboratory of Immune Signal, National Institute of Biomedical Innovation, Health and Nutrition, Ibaraki, Japan. ^[2] Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan; ttakahashi2@gesurg.med.osaka-u.ac.jp. ^[3] Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Japan. ^[4] Institute for Biomedical Scienwces Molecular Pathophysiology, Iwate Medical University, Shiwa-gun, Japan. ^[5] Division of Allergy and Rheumatology, Department of Internal Medicine, Iwate Medical University, Shiwa-gun, Japan. ^[6] Laboratory of Mockup Vaccine, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Ibaraki, Japan. ^[7] Division of Vaccine Science, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. ^[8] Laboratory of Immune Signal, National Institute of Biomedical Innovation, Health and Nutrition, Ibaraki, Japan; tnaka@iwate-med.ac.jp. ^[9]

关键词 Antitumor antibody CpG oligodeoxy-nucleotides glypican 1 macrophage natural killer cell