Surficial nano-deposition locoregionally yielding bactericidal super CAR-macrophages expedites periprosthetic osseointegration.

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作者： Ziyang,Li ^[1] ; Shengchang,Zhang ^[2] ; Zhipeng,Fu ^[3] ; Ying,Liu ^[1] ; Zhentao,Man ^[1] ; Chongdeng,Shi ^[1] ; Chunwei,Tang ^[2] ; Chen,Chen ^[3] ; Qihao,Chai ^[1] ; Zhenmei,Yang ^[1] ; Jing,Zhang ^[1] ; Xiaotian,Zhao ^[2] ; Hailun,Xu ^[1] ; Maosen,Han ^[1] ; Yan,Wang ^[1] ; Ziyang,Liao ^[3] ; Gongchang,Yu ^[1] ; Bin,Shi ^[1] ; Kun,Zhao ^[1] ; Wei,Li ^[4] ; Xinyi,Jiang ^[4]

作者单位： NMPA Key Laboratory for Technology Research and Evaluation of Drug Products and Key Laboratory of Chemical Biology (Ministry of Education), Department of Pharmaceutics, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, 44 Cultural West Road, Jinan, Shandong Province 250012, China. ^[1] Shandong Provincial Hospital, Shandong University, Jinan, Shandong Province 250021, China. ^[2] Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province 250021, China. ^[3] Neck-Shoulder and Lumbocrural Pain Hospital of Shandong First Medical University, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China. ^[4]

主题词动物(Animals);小鼠(Mice);金黄色葡萄球菌(Staphylococcus aureus);骨整合(Osseointegration);抗菌药(Anti-Bacterial Agents);巨噬细胞(Macrophages)

DOI 10.1126/sciadv.adg3365

PMID 37256944

发布时间 2023-08-12

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Science advances

2023年9卷22期

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Surficial nano-deposition locoregionally yielding bactericidal super CAR-macrophages expedites periprosthetic osseointegration.

Science advances

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Surficial nano-deposition locoregionally yielding bactericidal super CAR-macrophages expedites periprosthetic osseointegration.

Science advances

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Science advances

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