BET Bromodomain Degradation Disrupts Function but Not 3D Formation of RNA Pol2 Clusters.

导出 OA

翻译打印收藏纠错

第一作者： Diana H,Chin

第一单位： Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

作者： Diana H,Chin ^[1] ; Issra,Osman ^[1] ; Jadon,Porch ^[1] ; Hyunmin,Kim ^[1] ; Kristen K,Buck ^[2] ; Javier,Rodriguez ^[2] ; Bianca,Carapia ^[2] ; Deborah,Yan ^[2] ; Stela B,Moura ^[2] ; Jantzen,Sperry ^[2] ; Jonathan,Nakashima ^[2] ; Kasey,Altman ^[3] ; Delsee,Altman ^[3] ; Berkley E,Gryder ^[1]

作者单位： Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. ^[1] Certis Oncology Solutions, San Diego, CA 92121, USA. ^[2] Kasey Altman Research Fund, Rein in Sarcoma, Fridley, MN 55432, USA. ^[3] Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA. ^[4]

关键词 BET bromodomains BRD4 PAX3-FOXO1 RNA Polymerase II Rhabdomyosarcoma core regulatory circuitry transcription

DOI 10.3390/ph16020199

PMID 37259348

发布时间 2024-06-27

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交