Anti-melanoma Effects of Resiquimod (RSQ) In Vitro and in Combination with Immune Checkpoint Blockade In Vivo.

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作者： Supreeda,Tambunlertchai ^[1] ; Sean M,Geary ^[2] ; Youssef W,Naguib ^[1] ; Aliasger K,Salem ^[3]

作者单位： Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA. ^[1] Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA. sean-geary@uiowa.edu. ^[2] Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, 52242, USA. aliasger-salem@uiowa.edu. ^[3]

关键词 anti-PD-1 checkpoint blockade melanoma resiquimod (RSQ)tumor microenvironment

主题词小鼠(Mice);动物(Animals);黑色素瘤(Melanoma);皮肤肿瘤(Skin Neoplasms);免疫疗法(Immunotherapy);肿瘤微环境(Tumor Microenvironment)

DOI 10.1208/s12248-023-00824-3

PMID 37266761

发布时间 2024-09-25

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