A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis.

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作者： Takeshi,Imakura ^[1] ; Seidai,Sato ^[1] ; Kazuya,Koyama ^[1] ; Hirohisa,Ogawa ^[2] ; Takahiro,Niimura ^[3] ; Kojin,Murakami ^[1] ; Yuya,Yamashita ^[1] ; Keiko,Haji ^[1] ; Nobuhito,Naito ^[1] ; Kozo,Kagawa ^[1] ; Hiroshi,Kawano ^[1] ; Yoshito,Zamami ^[3] ; Keisuke,Ishizawa ^[4] ; Yasuhiko,Nishioka ^[3]

作者单位： Department of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan. ^[1] Department of Pathology and Laboratory Medicine, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan. ^[2] Department of Clinical Pharmacology and Therapeutics, Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan. ^[3] Department of Pharmacy, Okayama University Hospital, Okayama, Japan. ^[4] Department of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan. yasuhiko@tokushima-u.ac.jp. ^[5]

关键词 In silico screening Polo-like kinase Pulmonary fibrosis