Exosomal miR-17-92 derived from human mesenchymal stem cells promotes wound healing by enhancing angiogenesis and inhibiting endothelial cell ferroptosis.

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作者： Wenbo,Nie ^[1] ; Xuemiao,Huang ^[2] ; Lijing,Zhao ^[2] ; Taiwei,Wang ^[2] ; Dan,Zhang ^[2] ; Tianxin,Xu ^[2] ; Lin,Du ^[2] ; Yuxiang,Li ^[3] ; Weiyuan,Zhang ^[4] ; Fengjun,Xiao ^[5] ; Lisheng,Wang ^[6]

作者单位： Laboratory Management Office, Jilin University, Changchun, Jilin 130021, PR China; Department of Rehabilitation Sciences, School of Nursing, Jilin University, Changchun, Jilin 130021, PR China. ^[1] Department of Rehabilitation Sciences, School of Nursing, Jilin University, Changchun, Jilin 130021, PR China. ^[2] Department of Rehabilitation Sciences, School of Nursing, Jilin University, Changchun, Jilin 130021, PR China; Department of Molecular Diagnosis and Regenerative Medicine, Medical Research Center, the Affiliate Hospital of Qingdao University, Qingdao 266000, PR China. ^[3] Department of Molecular Diagnosis and Regenerative Medicine, Medical Research Center, the Affiliate Hospital of Qingdao University, Qingdao 266000, PR China. ^[4] Department of Experimental Hematology and Biochemistry, Beijing Institute of Radiation Medicine, Beijing 100850, PR China. Electronic address: xiaofjun@sina.com. ^[5] Department of Rehabilitation Sciences, School of Nursing, Jilin University, Changchun, Jilin 130021, PR China; Department of Experimental Hematology and Biochemistry, Beijing Institute of Radiation Medicine, Beijing 100850, PR China. Electronic address: lishengwang@jlu.edu.cn. ^[6]

关键词 Exosomes Mesenchymal stem cells MiR-17–92 Wound healing

主题词动物(Animals);人类(Humans);小鼠(Mice);外泌体(Exosomes);间质干细胞(Mesenchymal Stem Cells);微RNAs(MicroRNAs);伤口愈合(Wound Healing)

DOI 10.1016/j.tice.2023.102124

PMID 37269748

发布时间 2023-09-06

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