Super-enhancer-driven lncRNA Snhg7 aggravates cardiac hypertrophy via Tbx5/GLS2/ferroptosis axis.

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作者： Qianhui,Zhang ^[1] ; Chao,Song ^[2] ; Meitian,Zhang ^[1] ; Yongsheng,Liu ^[1] ; Lixin,Wang ^[1] ; Yawen,Xie ^[1] ; Hanping,Qi ^[1] ; Lina,Ba ^[1] ; Pilong,Shi ^[1] ; Yonggang,Cao ^[1] ; Hongli,Sun ^[3]

作者单位： Department of Pharmacology, Harbin Medical University-Daqing, Daqing, 163319, China. ^[1] The First Affiliated Hospital, Cardiovascular Lab of Big Data and Imaging Artificial Intelligence, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China. ^[2] Department of Pharmacology, Harbin Medical University-Daqing, Daqing, 163319, China. Electronic address: sunhongli@hmudq.edu.cn. ^[3]

关键词 Cardiac hypertrophy Ferroptosis LncRNA Snhg7 Nkx2-5 Super-enhancers Tbx5

主题词人类(Humans);心脏扩大(Cardiomegaly);转录因子(Transcription Factors);肌细胞, 心脏(Myocytes, Cardiac);微RNAs(MicroRNAs);谷氨酰胺酶(Glutaminase)

DOI 10.1016/j.ejphar.2023.175822

PMID 37277029

发布时间 2023-06-30

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