换一批Discovery of the First Potent, Selective, and <i>In Vivo</i> Efficacious Polo-like Kinase 4 Proteolysis Targeting Chimera Degrader for the Treatment of <i>TRIM37</i>-Amplified Breast Cancer.
第一作者：
Yin,Sun
第一单位：
Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, P.R. China.
作者：
医学主题词
人类(Humans);女(雌)性(Female);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);构效关系(Structure-Activity Relationship);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)
DOI
10.1021/acs.jmedchem.3c00505
PMID
37279162
发布时间
2023-06-27
- 浏览9
Journal of medicinal chemistry
8200-8221页
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