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首页> Structure (London, England : 1993)> A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.

A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.

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第一作者： Abner,Gonzalez

第一单位： Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

作者： Abner,Gonzalez ^[1] ; Hong Joo,Kim ^[2] ; Brian D,Freibaum ^[2] ; Ho Yee Joyce,Fung ^[1] ; Chad A,Brautigam ^[3] ; J Paul,Taylor ^[4] ; Yuh Min,Chook ^[5]

作者单位： Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[1] Department of Cell and Molecular Biology, St. Jude Children's Hospital, Memphis, TN, USA. ^[2] Departments of Biophysics and Microbiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ^[3] Department of Cell and Molecular Biology, St. Jude Children's Hospital, Memphis, TN, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. ^[4] Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: yuhmin.chook@utsouthwestern.edu. ^[5]

关键词 HNRNPH1 HNRNPH2 Karyopherin Neurodevelopmental disorder Nuclear Import PY-NLS Transportin-1 Transportin-2 hnRNP importin

主题词核胞浆转运蛋白类(Karyopherins);核定位信号(Nuclear Localization Signals);表位(Epitopes);酪氨酸(Tyrosine);脯氨酸(Proline);冷冻电子显微镜检查(Cryoelectron Microscopy);主动转运, 细胞核(Active Transport, Cell Nucleus);β核胞浆转运蛋白类(beta Karyopherins);细胞核(Cell Nucleus)

DOI 10.1016/j.str.2023.05.010

PMID 37279758

发布时间 2024-09-26

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Structure (London, England : 1993)

Structure (London, England

2023年31卷8期

924-934.e4页

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