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An overview of optimal designs under a given budget in cluster randomized trials with a binary outcome.

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第一作者： Jingxia,Liu

第一单位： Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine (WUSM), St Louis, Missouri, USA.;Division of Biostatistics, Washington University School of Medicine (WUSM), St Louis, Missouri, USA.

作者： Jingxia,Liu ^[1] ; Lei,Liu ^[2] ; Aimee S,James ^[3] ; Graham A,Colditz ^[3]

作者单位： Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine (WUSM), St Louis, Missouri, USA.;Division of Biostatistics, Washington University School of Medicine (WUSM), St Louis, Missouri, USA. ^[1] Division of Biostatistics, Washington University School of Medicine (WUSM), St Louis, Missouri, USA. ^[2] Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine (WUSM), St Louis, Missouri, USA. ^[3]

关键词 Cluster randomized trial MaxiMin design generalized estimating equation local optimal design partially nested design three-level parallel CRTs two-level parallel CRTs

医学主题词人类(Humans);聚类分析(Cluster Analysis);比值比(Odds Ratio);随机对照试验(主题)(Randomized Controlled Trials as Topic);研究设计(Research Design);样本大小(Sample Size)

DOI 10.1177/09622802231172026

PMID 37284817

发布时间 2026-04-22

基金项目

P50 CA244431/CA/NCI NIH HHS/United States U01 CA209861/CA/NCI NIH HHS/United States P30 CA091842/CA/NCI NIH HHS/United States UL1 TR000448/TR/NCATS NIH HHS/United States R01 CA233848/CA/NCI NIH HHS/United States UL1 TR002345/TR/NCATS NIH HHS/United States

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