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Emodin and rhapontigenin inhibit the replication of African swine fever virus by interfering with virus entry.

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第一作者： Yanchen,Guo

第一单位： Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, Research Center for African Swine Fever Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China; African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou 510642, China.

作者： Yanchen,Guo ^[1] ; Yang,Chen ^[1] ; Qiumei,Wang ^[1] ; Zhiyuan,Wang ^[1] ; Lang,Gong ^[2] ; Yankuo,Sun ^[2] ; Zebu,Song ^[1] ; Hao,Chang ^[1] ; Guihong,Zhang ^[3] ; Heng,Wang ^[4]

作者单位： Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, Research Center for African Swine Fever Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China; African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou 510642, China. ^[1] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, Research Center for African Swine Fever Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou 510642, China; Maoming Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming 525000, China; Key Laboratory of Animal Vaccine Development, Ministry of Agriculture and Rural Affairs, Guangzhou 510642, China. ^[2] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, Research Center for African Swine Fever Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou 510642, China; Maoming Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming 525000, China; Key Laboratory of Animal Vaccine Development, Ministry of Agriculture and Rural Affairs, Guangzhou 510642, China. Electronic address: guihongzh@scau.edu.cn. ^[3] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, Research Center for African Swine Fever Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou 510642, China; African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou 510642, China. Electronic address: wangheng2009@scau.edu.cn. ^[4]

关键词 ASFV Cholesterol Emodin Endosomal acidification Rab 7 Rhapontigenin