首页> Nature communications> Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies.

Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies.

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第一作者： Simona,Manni

第一单位： Department of Haematology-Oncology and Cell and Gene Therapy, Bambino Gesù Children Hospital, IRCCS, Rome, Italy.

作者： Simona,Manni ^[1] ; Francesca,Del Bufalo ^[1] ; Pietro,Merli ^[1] ; Domenico Alessandro,Silvestris ^[1] ; Marika,Guercio ^[1] ; Simona,Caruso ^[1] ; Sofia,Reddel ^[1] ; Laura,Iaffaldano ^[1] ; Michele,Pezzella ^[1] ; Stefano,Di Cecca ^[1] ; Matilde,Sinibaldi ^[1] ; Alessio,Ottaviani ^[1] ; Maria Cecilia,Quadraccia ^[1] ; Mariasole,Aurigemma ^[1] ; Andrea,Sarcinelli ^[1] ; Roselia,Ciccone ^[1] ; Zeinab,Abbaszadeh ^[1] ; Manuela,Ceccarelli ^[1] ; Rita,De Vito ^[2] ; Maria Chiara,Lodi ^[1] ; Maria Giuseppina,Cefalo ^[1] ; Angela,Mastronuzzi ^[1] ; Biagio,De Angelis ^[3] ; Franco,Locatelli ^[4] ; Concetta,Quintarelli ^[5]

作者单位： Department of Haematology-Oncology and Cell and Gene Therapy, Bambino Gesù Children Hospital, IRCCS, Rome, Italy. ^[1] Department of Pathological Anatomy, Bambino Gesù Children Hospital, IRCCS, Rome, Italy. ^[2] Department of Haematology-Oncology and Cell and Gene Therapy, Bambino Gesù Children Hospital, IRCCS, Rome, Italy. biagio.deangelis@opbg.net. ^[3] Department of Haematology-Oncology and Cell and Gene Therapy, Bambino Gesù Children Hospital, IRCCS, Rome, Italy. franco.locatelli@opbg.net.;Department of Pediatrics, Catholic University of the Sacred Heart, Rome, Italy. franco.locatelli@opbg.net. ^[4] Department of Haematology-Oncology and Cell and Gene Therapy, Bambino Gesù Children Hospital, IRCCS, Rome, Italy.;Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy. ^[5]