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Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer.

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第一作者： Krishan,Kumar

第一单位： Department of Internal Medicine, Division of Hematology, and Arthur G. James Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH 43210, USA.;Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.;Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA.

作者： Krishan,Kumar ^[1] ; Deepak,Kanojia ^[2] ; David J,Bentrem ^[3] ; Rosa F,Hwang ^[4] ; Jonathan P,Butchar ^[5] ; Susheela,Tridandapani ^[5] ; Hidayatullah G,Munshi ^[6]

作者单位： Department of Internal Medicine, Division of Hematology, and Arthur G. James Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH 43210, USA.;Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.;Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA. ^[1] Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. ^[2] Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA.;Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.;Jesse Brown VA Medical Center, Chicago, IL 60612, USA. ^[3] Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[4] Department of Internal Medicine, Division of Hematology, and Arthur G. James Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH 43210, USA. ^[5] Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.;Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA.;Jesse Brown VA Medical Center, Chicago, IL 60612, USA. ^[6]

关键词 BET inhibitors BRD2 HYAL1 apoptosis bromodomain and extra-terminal (BET) proteins hyaluronidases pancreatic cancer proliferation