首页> Chemical engineering journal (Lausanne, Switzerland : 1996)> Polymeric micelles amplify tumor oxidative stresses through combining PDT and glutathione depletion for synergistic cancer chemotherapy.

Polymeric micelles amplify tumor oxidative stresses through combining PDT and glutathione depletion for synergistic cancer chemotherapy.

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第一作者： Ting,Su

第一单位： Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.;National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.;Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, Institute for Structural Biology and Drug Discovery, School of Pharmacy, The Developmental Therapeutics Program, Massey Cancer Center, Richmond, VA 23298, USA.

作者： Ting,Su ^[1] ; Furong,Cheng ^[2] ; Yuji,Pu ^[3] ; Jun,Cao ^[3] ; Shuibin,Lin ^[4] ; Guizhi,Zhu ^[5] ; Bin,He ^[3]

作者单位： Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.;National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.;Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, Institute for Structural Biology and Drug Discovery, School of Pharmacy, The Developmental Therapeutics Program, Massey Cancer Center, Richmond, VA 23298, USA. ^[1] Center for Translational Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China.;National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.;Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, Institute for Structural Biology and Drug Discovery, School of Pharmacy, The Developmental Therapeutics Program, Massey Cancer Center, Richmond, VA 23298, USA. ^[2] National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China. ^[3] Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. ^[4] Department of Pharmaceutics and Center for Pharmaceutical Engineering and Sciences, Institute for Structural Biology and Drug Discovery, School of Pharmacy, The Developmental Therapeutics Program, Massey Cancer Center, Richmond, VA 23298, USA. ^[5]

关键词 Arylboronic esters Combination cancer therapy GSH depletion Photodynamic therapy Polymeric micelle

DOI 10.1016/j.cej.2021.128561

PMID 37304676

发布时间 2023-07-01

基金项目

R35 GM143014/GM/NIGMS NIH HHS/United States UL1 TR002649/TR/NCATS NIH HHS/United States R21 NS114455/NS/NINDS NIH HHS/United States P30 NS047463/NS/NINDS NIH HHS/United States P30 CA016059/CA/NCI NIH HHS/United States KL2 TR002648/TR/NCATS NIH HHS/United States

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