The Power of Kinetic Inertness in Improving Platinum Anticancer Therapy by Circumventing Resistance and Ameliorating Nephrotoxicity.

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作者： Tushar Ranjan,Panda ^[1] ; Manikandan,M ^[1] ; Shreyas P,Vaidya ^[1] ; Sushanta,Chhatar ^[1] ; Suman,Sinha ^[2] ; Megha,Mehrotra ^[3] ; Sourav,Chakraborty ^[4] ; Shubhankar,Gadre ^[3] ; Prakash,Duari ^[4] ; Pritha,Ray ^[1] ; Malay,Patra ^[1]

作者单位： Laboratory of Medicinal Chemistry and Cell Biology, Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Navy Nagar, 400005, Mumbai, India. ^[1] Institute of Pharmaceutical Research, GLA University, 7 km Stone, NH-2, Mathura-Delhi Road, Mathura, Uttar Pradesh, 281406, India. ^[2] Imaging Cell Signaling & Therapeutics Lab, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Sector 22, Kharghar, Navi Mumbai, 410210, Maharashtra, India. ^[3] Homi Bhabha National Institute, 2nd floor, BARC Training School Complex Anushaktinagar, Mumbai, 400094, Maharashtra, India. ^[4]

关键词 Antitumor Effect Kinetic Inertness Nephrotoxicity Platinum Drugs Platinum Resistance

主题词人类(Humans);铂(Platinum);顺铂(Cisplatin);抗肿瘤药(Antineoplastic Agents);肿瘤(Neoplasms);动力学(Kinetics);细胞系, 肿瘤(Cell Line, Tumor)

DOI 10.1002/anie.202303958

PMID 37314332

发布时间 2023-10-13

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准确一般字义偏差语意偏离译文作用小提交