Ligustilide, a novel SIRT1 agonist, alleviates lipopolysaccharide-induced acute lung injury through deacetylation of NICD.

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作者： Guang,Li ^[1] ; Chunxiao,Hu ^[2] ; Yan,Liu ^[3] ; Huiqing,Lin ^[4]

作者单位： Department of Critical Care Medicine, Renmin Hospital, Wuhan University, Wuhan, Hubei Province, China. ^[1] Department of Transplant Anesthesiology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, China. ^[2] Department of Thoracic Surgery, Renmin Hospital, Wuhan University, Wuhan, Hubei Province, China. ^[3] Department of Thoracic Surgery, Renmin Hospital, Wuhan University, Wuhan, Hubei Province, China. Electronic address: huiqing.lin@whu.edu.cn. ^[4]

关键词 Acute lung injury Ligustilide NICD SIRT1

主题词动物(Animals);小鼠(Mice);急性肺损伤(Acute Lung Injury);炎症(Inflammation);脂多糖类(Lipopolysaccharides);肺(Lung);脓毒症(Sepsis);抗衰老酶1(Sirtuin 1);受体, Notch1(Receptor, Notch1)

DOI 10.1016/j.intimp.2023.110486

PMID 37327514

发布时间 2023-11-08

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International immunopharmacology

2023年121卷

110486页

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Ligustilide, a novel SIRT1 agonist, alleviates lipopolysaccharide-induced acute lung injury through deacetylation of NICD.

International immunopharmacology

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International immunopharmacology

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Ligustilide, a novel SIRT1 agonist, alleviates lipopolysaccharide-induced acute lung injury through deacetylation of NICD.

International immunopharmacology

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International immunopharmacology

相关期刊

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