Effect of alirocumab on cataracts in patients with acute coronary syndromes.

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第一作者： Gaspard,Suc

第一单位： Université Paris-Cité, INSERM_U1148/LVTS, Paris, France.

作者： Gaspard,Suc ^[1] ; Gregory G,Schwartz ^[2] ; Shaun G,Goodman ^[3] ; J Wouter,Jukema ^[4] ; Garen,Manvelian ^[5] ; Yann,Poulouin ^[6] ; Robert,Pordy ^[7] ; Michel,Scemama ^[8] ; Michael,Szarek ^[9] ; Ph Gabriel,Steg ^[8] ; ODYSSEY OUTCOMES Investigators ^[10]

作者单位： Université Paris-Cité, INSERM_U1148/LVTS, Paris, France. ^[1] Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, Paris, France. ^[2] Division of Cardiology, University of Colorado School of Medicine, Aurora, CO, USA. ^[3] Canadian VIGOUR Centre, University of Alberta, Edmonton, AB, Canada. ^[4] St. Michael's Hospital, University of Toronto, Toronto, ON, Canada. ^[5] Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. ^[6] Netherlands Heart Institute, Utrecht, the Netherlands. ^[7] Regeneron Pharmaceuticals, Tarrytown, NY, USA. ^[8] IT&M Stats, Neuilly-sur-Seine, France. ^[9] Sanofi, Chilly-Mazarin, France. ^[10] Downstate School of Public Health, State University of New York, Brooklyn, NY, USA. ^[11] CPC Clinical Research and Division of Cardiology, University of Colorado School of Medicine, Aurora, CO, USA. ^[12] Université Paris-Cité, INSERM_U1148/LVTS, Paris, France. gabriel.steg@aphp.fr. ^[13] Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, Paris, France. gabriel.steg@aphp.fr. ^[14] Institut Universitaire de France, Paris, France. gabriel.steg@aphp.fr. ^[15] FACT (French Alliance for Cardiovascular Trials), INSERM U-1148, Paris, France. gabriel.steg@aphp.fr. ^[16] Département de Cardiologie, AP-HP Hôpital Bichat, 46 Rue Henri Huchard, Paris, 75018, France. gabriel.steg@aphp.fr. ^[17]

关键词 Acute coronary syndrome Alirocumab Cataracts PCSK9 inhibitor

主题词人类(Humans);胆固醇, LDL(Cholesterol, LDL);急性冠状动脉综合征(Acute Coronary Syndrome);羟甲基戊二酰基CoA还原酶抑制剂(Hydroxymethylglutaryl-CoA Reductase Inhibitors);白内障(Cataract);治疗结果(Treatment Outcome);双盲法(Double-Blind Method)

DOI 10.1186/s12886-023-03012-1

PMID 37328736

发布时间 2023-07-06

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