Comprehensive analysis identifies cuproptosis-related gene DLAT as a potential prognostic and immunological biomarker in pancreatic adenocarcinoma.

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第一作者： Xiaoling,Zhang

第一单位： Department of Digestive Internal Medicine, Harbin Medical University Cancer Hospital, Harbin, 150081, China.

作者： Xiaoling,Zhang ^[1] ; Yuxin,Zhou ^[1] ; Jiahe,Hu ^[1] ; Xuefeng,Yu ^[2] ; Haitao,Xu ^[3] ; Zhichang,Ba ^[4] ; Haoxin,Zhang ^[1] ; Yanan,Sun ^[1] ; Rongfang,Wang ^[1] ; Xinlian,Du ^[1] ; Ruishu,Mou ^[1] ; Xuedong,Li ^[1] ; Jiuxin,Zhu ^[5] ; Rui,Xie ^[6]

作者单位： Department of Digestive Internal Medicine, Harbin Medical University Cancer Hospital, Harbin, 150081, China. ^[1] Department of Gastroenterological Surgery, Harbin Medical University Cancer Hospital, Harbin, 150081, China. ^[2] Department of Hepatobiliary and Pancreatic Surgery, Harbin Medical University Cancer Hospital, Harbin, 150081, China. ^[3] Medical Imaging Center, Harbin Medical University Cancer Hospital, Harbin, 150081, China. ^[4] Department of Pharmacology (National Key Laboratory of Frigid Zone Cardiovascular Diseases, State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. zhujiuxin@hrbmu.edu.cn. ^[5] Department of Digestive Internal Medicine, Harbin Medical University Cancer Hospital, Harbin, 150081, China. rxie@hrbmu.edu.cn. ^[6]

关键词 Cuproptosis DLAT Immunotherapy Pancreatic adenocarcinoma Prognosis

主题词人类(Humans);预后(Prognosis);腺癌(Adenocarcinoma);胰腺肿瘤(Pancreatic Neoplasms);二氢硫辛酰赖氨酸-残基乙酰转移酶(Dihydrolipoyllysine-Residue Acetyltransferase);铜(Copper);细胞凋亡(Apoptosis)

DOI 10.1186/s12885-023-11042-7

PMID 37330494

发布时间 2023-12-13

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