Deciphering the causal relationship between blood pressure and regional white matter integrity: A two-sample Mendelian randomization study.

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第一作者： Zhenyao,Ye

第一单位： Maryland Psychiatric Research Center, Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, Maryland, USA.;Division of Biostatistics and Bioinformatics, Department of Epidemiology and Public Health, School of Medicine, University of Maryland, Baltimore, Maryland, USA.

作者： Zhenyao,Ye ^[1] ; Chen,Mo ^[2] ; Song,Liu ^[3] ; Si,Gao ^[4] ; Li,Feng ^[5] ; Boao,Zhao ^[6] ; Travis,Canida ^[7] ; Yu-Chia,Wu ^[6] ; Kathryn S,Hatch ^[4] ; Yizhou,Ma ^[4] ; Braxton D,Mitchell ^[8] ; L Elliot,Hong ^[4] ; Peter,Kochunov ^[4] ; Chixiang,Chen ^[9] ; Bingxin,Zhao ^[10] ; Shuo,Chen ^[1] ; Tianzhou,Ma ^[6]

作者单位： Maryland Psychiatric Research Center, Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, Maryland, USA.;Division of Biostatistics and Bioinformatics, Department of Epidemiology and Public Health, School of Medicine, University of Maryland, Baltimore, Maryland, USA. ^[1] Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA. ^[2] School of Computer Science and Technology, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China. ^[3] Maryland Psychiatric Research Center, Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, Maryland, USA. ^[4] Department of Nutrition and Food Science, College of Agriculture & Natural Resources, University of Maryland, College Park, Maryland, USA. ^[5] Department of Epidemiology and Biostatistics, School of Public Health, University of Maryland, College Park, Maryland, USA. ^[6] Department of Mathematics, The College of Computer, Mathematical, and Natural Sciences, University of Maryland, College Park, Maryland, USA. ^[7] Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA. ^[8] Division of Biostatistics and Bioinformatics, Department of Epidemiology and Public Health, School of Medicine, University of Maryland, Baltimore, Maryland, USA. ^[9] Department of Statistics, Purdue University, West Lafayette, Indiana, USA. ^[10]

关键词 Mendelian randomization blood pressure diffusion tensor imaging genome-wide association study white matter

主题词人类(Humans);中年人(Middle Aged);血压(Blood Pressure);弥散张量成像(Diffusion Tensor Imaging);孟德尔随机化分析(Mendelian Randomization Analysis);全基因组关联研究(Genome-Wide Association Study);多态性, 单核苷酸(Polymorphism, Single Nucleotide)

DOI 10.1002/jnr.25205

PMID 37330925

发布时间 2024-09-02

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