Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites.

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作者： Péter,Angyal ^[1] ; Kristóf,Hegedüs ^[2] ; Bence Balázs,Mészáros ^[1] ; János,Daru ^[2] ; Ádám,Dudás ^[1] ; Anna Rita,Galambos ^[3] ; Nariman,Essmat ^[1] ; Mahmoud,Al-Khrasani ^[2] ; Szilárd,Varga ^[4] ; Tibor,Soós ^[4]

作者单位： Institute of Organic Chemistry, Research Centre for Natural Sciences, Magyar tudósok körútja 2, 1117, Budapest, Hungary. ^[1] Hevesy György PhD School of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, 1117, Budapest, Hungary. ^[2] Department of Chemistry, Eötvös Loránd University, Pázmány Péter sétány 1/A, 1117, Budapest, Hungary. ^[3] Department of Pharmacology and Pharmacotherapy, Semmelweis University, Nagyvárad tér 4, 1089, Budapest, Hungary. ^[4]

关键词 Biological Activity Chiral Pool Medicinal Chemistry Natural Products Total Synthesis

主题词帽柱木属(Mitragyna);裂环马钱素色胺生物碱类(Secologanin Tryptamine Alkaloids);镇痛药, 阿片类(Analgesics, Opioid)

DOI 10.1002/anie.202303700

PMID 37332089

发布时间 2023-08-24

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准确一般字义偏差语意偏离译文作用小提交