Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation.

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作者： Sandra L,Grimm ^[1] ; Rachel E,Stading ^[2] ; Matthew J,Robertson ^[3] ; Tanmay,Gandhi ^[3] ; Chenlian,Fu ^[4] ; Weiwu,Jiang ^[2] ; Guobin,Xia ^[2] ; Krithika,Lingappan ^[5] ; Cristian,Coarfa ^[6] ; Bhagavatula,Moorthy ^[7]

作者单位： Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA; Dept. of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA. ^[1] Division of Neonatology, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA. ^[2] Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA. ^[3] Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA; Mathematical and Computational Biology, Harvey Mudd College, CA, USA. ^[4] Division of Neonatology at Children's Hospital of Philadelphia, USA. ^[5] Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA; Dept. of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA. Electronic address: coarfa@bcm.edu. ^[6] Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA; Division of Neonatology, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA. Electronic address: bmoorthy@bcm.edu. ^[7]

关键词 Bronchopulmonary dysplasia CYP1B1 Cytochrome P450 Hyperoxia Lung Oxidative stress

主题词人类(Humans);婴儿, 新生(Infant, Newborn);动物(Animals);小鼠(Mice);高氧症(Hyperoxia);细胞色素P450 CYP1A2(Cytochrome P-450 CYP1A2);肺损伤(Lung Injury);细胞色素P450 CYP1A1(Cytochrome P-450 CYP1A1);小鼠, 近交C57BL(Mice, Inbred C57BL);氧(Oxygen);支气管肺发育不良(Bronchopulmonary Dysplasia);小鼠, 基因敲除(Mice, Knockout);肺(Lung);动物, 新生(Animals, Newborn)

DOI 10.1016/j.redox.2023.102790

PMID 37348155

发布时间 2024-02-11

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Redox biology

2023年64卷

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Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation.

Redox biology

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Redox biology

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Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation.

Redox biology

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Redox biology

相关期刊

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