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Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections.

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第一作者: Wanwisa,Promsote
第一单位: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
作者单位: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. [1] Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.;ModeX Therapeutics Inc., 22 Strathmore Road, Natick, MA, 01760, USA. [2] Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA. [3] Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA.;Perspix Biotech GmbH, FiZ Frankfurt Innovation Center Biotechnology, Altenhoeferallee 3, 60438, Frankfurt, Germany. [4] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.;Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital (chuv) and University of Lausanne, Lausanne, Switzerland. [5] NIAID, NIH, Bethesda, MD, 20892, USA. [6] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.;ModeX Therapeutics Inc., 22 Strathmore Road, Natick, MA, 01760, USA. [7] Sanofi, 640 Memorial Dr., Cambridge, MA, 02139, USA. gary.nabel@modextx.com.;ModeX Therapeutics Inc., 22 Strathmore Road, Natick, MA, 01760, USA. gary.nabel@modextx.com. [8] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. rkoup@nih.gov. [9]
DOI 10.1038/s41467-023-39265-z
PMID 37349337
发布时间 2023-11-17
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