首页> Vaccine> Intramuscular administration of recombinant Newcastle disease virus expressing SARS-CoV-2 spike protein protects hACE-2 TG mice against SARS-CoV-2 infection.

Intramuscular administration of recombinant Newcastle disease virus expressing SARS-CoV-2 spike protein protects hACE-2 TG mice against SARS-CoV-2 infection.

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第一作者： Deok-Hwan,Kim

第一单位： Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea; KHAV Co., Ltd., 1 Hwayang-dong, Gwangjin-gu, Seoul, Republic of Korea.

作者： Deok-Hwan,Kim ^[1] ; Jiho,Lee ^[2] ; Sungsu,Youk ^[3] ; Jei-Hyun,Jeong ^[1] ; Da-Ye,Lee ^[4] ; Hyo-Seon,Ju ^[4] ; Ha-Na,Youn ^[4] ; Jin-Cheol,Kim ^[4] ; Soo-Bin,Park ^[4] ; Ji-Eun,Park ^[4] ; Ji-Yun,Kim ^[4] ; Tae-Hyeon,Kim ^[2] ; Seung-Hun,Lee ^[4] ; Hyukchae,Lee ^[2] ; Lah,Mouhamed Abdallah Amal Abdal ^[2] ; Dong-Hun,Lee ^[5] ; Pil-Gu,Park ^[6] ; Kee-Jong,Hong ^[6] ; Chang-Seon,Song ^[7]

作者单位： Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea; KHAV Co., Ltd., 1 Hwayang-dong, Gwangjin-gu, Seoul, Republic of Korea. ^[1] Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea. ^[2] Department of Microbiology, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea. ^[3] KHAV Co., Ltd., 1 Hwayang-dong, Gwangjin-gu, Seoul, Republic of Korea. ^[4] Wildlife Health Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea. ^[5] Department of Microbiology, College of Medicine, Gachon University, Incheon, Republic of Korea. ^[6] Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea; KHAV Co., Ltd., 1 Hwayang-dong, Gwangjin-gu, Seoul, Republic of Korea. Electronic address: songcs@konkuk.ac.kr. ^[7]

关键词 Intramuscular vaccine K18-hACE-2 TG mice Lung viral load Newcastle disease virus-vectored vaccine SARS-CoV-2