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Multi-omics dissection of stage-specific artemisinin tolerance mechanisms in Kelch13-mutant Plasmodium falciparum.

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作者: Jiayun,Chen [1] ; Peng,Gao [2] ; Wei,Xiao [3] ; Guangqing,Cheng [2] ; Sanjeev,Krishna [4] ; Jianyou,Wang [2] ; Yin Kwan,Wong [5] ; Chen,Wang [2] ; Liwei,Gu [2] ; Dong Hua,Yang [6] ; Jigang,Wang [7]
作者单位: Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; Department of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People's Hospital, First Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518020, Guangdong, China. [1] Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. [2] Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education, Guangdong Pharmaceutical University, Guangzhou 510006, Guangdong, China. [3] Clinical Academic Group in Institute for Infection & Immunity, St George's University of London, London, United Kingdom; St George's University Hospitals NHS Foundation Trust, United Kingdom; Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany. [4] Department of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People's Hospital, First Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518020, Guangdong, China. [5] New York College of Traditional Chinese Medicine Mineola, United States. Electronic address: Yangd1@stjohns.edu. [6] Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; Department of Critical Medicine, and Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People's Hospital, First Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518020, Guangdong, China. Electronic address: jgwang@icmm.ac.cn. [7]
DOI 10.1016/j.drup.2023.100978
PMID 37385107
发布时间 2023-08-15
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