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CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process.

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第一作者： Bianca,Altvater

第一单位： Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany.

作者： Bianca,Altvater ^[1] ; Sareetha,Kailayangiri ^[1] ; Christian,Spurny ^[1] ; Maike,Flügge ^[1] ; Jutta,Meltzer ^[1] ; Lea,Greune ^[1] ; Katja,Urban ^[1] ; Christian,Schwöppe ^[2] ; Caroline,Brand ^[2] ; Christoph,Schliemann ^[2] ; Heike,Hintelmann ^[2] ; Saliha,Harrach ^[2] ; Wolfgang,Hartmann ^[3] ; Hinrich,Abken ^[4] ; Johannes,Kuehle ^[5] ; Axel,Schambach ^[6] ; Dennis,Görlich ^[7] ; Wolfgang E,Berdel ^[8] ; Claudia,Rossig ^[9]

作者单位： Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany. ^[1] Department of Medicine A, University of Muenster, Muenster, Germany. ^[2] Division of Translational Pathology, Gerhard-Domagk-Institute of Pathology, Münster University Hospital, Münster, Germany. ^[3] Division of Genetic Immunotherapy, Leibniz Institute for Immunotherapy (LIT), and University of Regensburg, Regensburg, Germany. ^[4] Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany. ^[5] Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.;REBIRTH Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, Germany.;Division of Hematology/Oncology, Harvard Medical School, Boston Children's Hospital, Boston, MA, USA. ^[6] Institute of Biostatistics and Clinical Research, University of Muenster, Muenster, Germany. ^[7] Department of Medicine A, University of Muenster, Muenster, Germany.;Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Muenster, Muenster, Germany. ^[8] Department of Pediatric Hematology and Oncology, University Children's Hospital Muenster, Muenster, Germany. rossig@ukmuenster.de.;Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Muenster, Muenster, Germany. rossig@ukmuenster.de.;Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. rossig@ukmuenster.de. ^[9]