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Mu Opioid Receptor-Positive Neurons in the Dorsal Raphe Nucleus Are Impaired by Morphine Abstinence.

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第一作者： Lola,Welsch

第一单位： Douglas Research Center, Department of Psychiatry, McGill University, Montréal, Quebec, Canada; INSERM U1114, University of Strasbourg, Strasbourg, France.

作者： Lola,Welsch ^[1] ; Esther,Colantonio ^[2] ; Camille,Falconnier ^[3] ; Cédric,Champagnol-DiLiberti ^[2] ; Florence,Allain ^[1] ; Sami,Ben Hamida ^[4] ; Emmanuel,Darcq ^[1] ; Pierre-Eric,Lutz ^[5] ; Brigitte L,Kieffer ^[6]

作者单位： Douglas Research Center, Department of Psychiatry, McGill University, Montréal, Quebec, Canada; INSERM U1114, University of Strasbourg, Strasbourg, France. ^[1] INSERM U1114, University of Strasbourg, Strasbourg, France. ^[2] Centre National de la Recherche Scientifique, Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives UPR3212, Strasbourg, France. ^[3] Douglas Research Center, Department of Psychiatry, McGill University, Montréal, Quebec, Canada; INSERM UMR 1247, Research Group on Alcohol & Pharmacodependences, Université de Picardie Jules Verne, Amiens, France. ^[4] Douglas Research Center, Department of Psychiatry, McGill University, Montréal, Quebec, Canada; Centre National de la Recherche Scientifique, Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives UPR3212, Strasbourg, France. ^[5] Douglas Research Center, Department of Psychiatry, McGill University, Montréal, Quebec, Canada; INSERM U1114, University of Strasbourg, Strasbourg, France. Electronic address: brigitte.kieffer@unistra.fr. ^[6]

关键词 Addiction-related behaviors Chronic morphine Mu opioid signaling Opto-intracranial self-stimulation vTRAP-seq

医学主题词小鼠(Mice);动物(Animals);吗啡(Morphine);受体, 阿片样, μ(Receptors, Opioid, mu);镇痛药, 阿片类(Analgesics, Opioid);神经元(Neurons)

DOI 10.1016/j.biopsych.2023.06.024

PMID 37393045

发布时间 2024-02-10

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