Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress.

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第一作者： Abner T,Apsley

第一单位： Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA, USA.;Department of Molecular, Cellular and Integrative Biological Sciences, The Pennsylvania State University, University Park, PA, USA.

作者： Abner T,Apsley ^[1] ; Qiaofeng,Ye ^[2] ; Laura,Etzel ^[2] ; Sarah,Wolf ^[2] ; Waylon J,Hastings ^[3] ; Brooke C,Mattern ^[2] ; Sue Rutherford,Siegel ^[2] ; Idan,Shalev ^[2]

作者单位： Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA, USA.;Department of Molecular, Cellular and Integrative Biological Sciences, The Pennsylvania State University, University Park, PA, USA. ^[1] Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA, USA. ^[2] Department of Psychiatry, Tulane University School of Medicine, New Orleans, LA, USA. ^[3]

关键词 DNA methylation acute psychosocial stress early-life adversity epigenetic clocks immune cell estimators stability temporal dynamics

主题词 DNA甲基化(DNA Methylation);时间因素(Time Factors);基因组学(Genomics);应激, 心理学(Stress, Psychological);衰老(Aging);后成说, 遗传(Epigenesis, Genetic)

DOI 10.1080/15592294.2023.2230686

PMID 37393564

发布时间 2024-04-23

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