Phase variation as a major mechanism of adaptation in <i>Mycobacterium tuberculosis</i> complex.

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作者： Roger,Vargas ^[1] ; Michael J,Luna ^[2] ; Luca,Freschi ^[3] ; Maximillian,Marin ^[2] ; Ruby,Froom ^[2] ; Kenan C,Murphy ^[4] ; Elizabeth A,Campbell ^[5] ; Thomas R,Ioerger ^[3] ; Christopher M,Sassetti ^[4] ; Maha Reda,Farhat ^[6]

作者单位： Center for Computational Biomedicine, Harvard Medical School, Boston, MA 02115. ^[1] Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115. ^[2] Department of Microbiology and Physiological Systems, University of Massachusetts Chan Medical School, Worcester, MA 01655. ^[3] Laboratory of Molecular Biophysics, The Rockefeller University, New York, NY 10065. ^[4] Laboratory of Host-Pathogen Biology, The Rockefeller University, New York, NY 10065. ^[5] Department of Computer Science and Engineering, Texas A&M University, College Station, TX 77843. ^[6] Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA 02114. ^[7]

关键词 genomics microbiology phase variation tuberculosis

主题词结核分枝杆菌(Mycobacterium tuberculosis);基因组学(Genomics);适应, 生理学(Adaptation, Physiological);毒力(Virulence);种系发生(Phylogeny);基因组, 细菌(Genome, Bacterial)

DOI 10.1073/pnas.2301394120

PMID 37399390

发布时间 2024-02-24

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准确一般字义偏差语意偏离译文作用小提交