Tumor-mediated microbiota alteration impairs synaptic tagging/capture in the hippocampal CA1 area via IL-1β production.

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作者： Ying,Zhu ^[1] ; Yu,Mei ^[1] ; Nimmi,Baby ^[2] ; Huey Yee,Teo ^[1] ; Zuhairah,Binte Hanafi ^[1] ; Siti Nazihah,Mohd Salleh ^[3] ; Sreedharan,Sajikumar ^[4] ; Haiyan,Liu ^[5]

作者单位： Immunology Translational Research Programme, Department of Microbiology of Immunology, Yong Loo Lin School of Medicine, Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore. ^[1] Department of Physiology, National University of Singapore, Singapore, 117597, Singapore. ^[2] Human Monoclonal Antibody Platform, Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, 138648, Singapore. ^[3] Department of Physiology, National University of Singapore, Singapore, 117597, Singapore. phssks@nus.edu.sg. ^[4] Life Sciences Institute Neurobiology Programme, National University of Singapore, Singapore, 117456, Singapore. phssks@nus.edu.sg. ^[5] Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore. phssks@nus.edu.sg. ^[6] Immunology Translational Research Programme, Department of Microbiology of Immunology, Yong Loo Lin School of Medicine, Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore. micliuh@nus.edu.sg. ^[7]

主题词动物(Animals);小鼠(Mice);癌, 肝细胞(Carcinoma, Hepatocellular);肝肿瘤(Liver Neoplasms);CA1区, 海马(CA1 Region, Hippocampal);认知(Cognition)

DOI 10.1038/s42003-023-05036-1

PMID 37400621

发布时间 2023-07-10

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Communications biology

2023年6卷1期

685页

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Tumor-mediated microbiota alteration impairs synaptic tagging/capture in the hippocampal CA1 area via IL-1β production.

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Tumor-mediated microbiota alteration impairs synaptic tagging/capture in the hippocampal CA1 area via IL-1β production.

Communications biology

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Communications biology

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