Bioprinted Multicomponent Hydrogel Co-culture Tumor-Immune Model for Assessing and Simulating Tumor-Infiltrated Lymphocyte Migration and Functional Activation.

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作者： Salvador,Flores-Torres ^[1] ; Nikolaos M,Dimitriou ^[1] ; Lucas Antonio,Pardo ^[1] ; Jacqueline,Kort-Mascort ^[1] ; Sanjima,Pal ^[2] ; Omar,Peza-Chavez ^[1] ; Hellen,Kuasne ^[3] ; Julie,Berube ^[2] ; Nicholas,Bertos ^[4] ; Morag,Park ^[5] ; Georgios D,Mitsis ^[6] ; Lorenzo,Ferri ^[7] ; Veena,Sangwan ^[8] ; Joseph M,Kinsella ^[1]

作者单位： Department of Bioengineering, McGill University, Montreal H3A 0G4, Quebec, Canada. ^[1] Department of Surgery, McGill University, Montreal H3A 0G4, Quebec, Canada. ^[2] Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal H3A 0G4, Quebec, Canada. ^[3] Research Institute of the McGill University Health Centre (RI-MUHC), Montreal H3G 2M1, Quebec, Canada. ^[4] Department of Biochemistry, McGill University, Montreal H3A 0G4, Quebec, Canada. ^[5] Department of Medicine, McGill University, Montreal H3A 0G4, Quebec, Canada. ^[6] Department of Oncology, McGill University, Montreal H3A 0G4, Quebec, Canada. ^[7] Department of Pathology, McGill University, Montreal H3A 0G4, Quebec, Canada. ^[8]

关键词 bioprinting tumor immune microenvironment tumor infiltrated lymphocytes

主题词人类(Humans);共同培养技术(Coculture Techniques);淋巴细胞, 肿瘤浸润(Lymphocytes, Tumor-Infiltrating);纵向研究(Longitudinal Studies);水凝胶类(Hydrogels);肿瘤(Neoplasms);细胞运动(Cell Movement)

DOI 10.1021/acsami.3c02995

PMID 37404007

发布时间 2023-07-21

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