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Dasatinib with intensive chemotherapy in de novo paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (CA180-372/COG AALL1122): a single-arm, multicentre, phase 2 trial.

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第一作者: Stephen P,Hunger
第一单位: Department of Pediatrics and The Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA; The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: hungers@chop.edu.
作者单位: Department of Pediatrics and The Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA; The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: hungers@chop.edu. [1] Division of Pediatric Hematology-Oncology, Charles Bruneau Cancer Center, CHU Sainte-Justine, University of Montreal, Montreal, QC, Canada. [2] Children's Cancer Group, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK; Tata Translational Cancer Research Centre, Tata Medical Center, Kolkata, India. [3] Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, TN, USA. [4] Biostatistics and Clinical Epidemiology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy. [5] Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA; Department of Pathology, Ohio State University College of Medicine, Columbus, OH, USA. [6] Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy; Genetics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy. [7] Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA. [8] Department of Pathology and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. [9] Leukaemia Research Cytogenetics Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK. [10] Department of Pathology, Ohio State University College of Medicine, Columbus, OH, USA. [11] Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA. [12] Bristol-Myers Squibb, Princeton, NJ, USA. [13] Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA, USA; Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA, USA. [14] Department of Pediatrics and Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA. [15] Pediatric Hematology-Oncology, British Columbia Children's Hospital, Vancouver, BC, Canada. [16] Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA. [17] Department of Pediatrics, University Medical Center Schleswig-Holstein, Kiel, Germany. [18] Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Division of Pediatric Hematology-Oncology, Boston Children's Hospital, Boston, MA, USA. [19] Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy. [20]
DOI 10.1016/S2352-3026(23)00088-1
PMID 37407142
发布时间 2023-07-18
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The Lancet. Haematology

The Lancet. Haematology

2023年10卷7期

e510-e520页

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