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CDK4/6-MEK Inhibition in MPNSTs Causes Plasma Cell Infiltration, Sensitization to PD-L1 Blockade, and Tumor Regression.

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第一作者: Jordan L,Kohlmeyer
第一单位: Molecular Medicine Graduate Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
作者单位: Molecular Medicine Graduate Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [1] Cancer Biology Graduate Program, University of Iowa, Iowa City, Iowa.;Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa. [2] Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [3] Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [4] Cancer Biology Graduate Program, University of Iowa, Iowa City, Iowa.;Medical Scientist Training Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [5] Cancer Biology Graduate Program, University of Iowa, Iowa City, Iowa.;Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.;Medical Scientist Training Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [6] Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa. [7] Cancer Biology Graduate Program, University of Iowa, Iowa City, Iowa. [8] Molecular Medicine Graduate Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [9] Department of Microbiology and Molecular Cell Biology, Leroy T. Canoles Jr. Cancer Center, Eastern Virginia Medical School, Norfolk, Virginia. [10] Department of Oncology, Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland. [11] Division of Medical Oncology, Washington University, St. Louis, Missouri. [12] Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [13] Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.;Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa. [14] Iowa Institute of Human Genetics, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [15] Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.;Department of Radiation, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [16] Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.;Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [17] Molecular Medicine Graduate Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Cancer Biology Graduate Program, University of Iowa, Iowa City, Iowa.;Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.;Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [18] Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.;Medical Scientist Training Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [19] Molecular Medicine Graduate Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Cancer Biology Graduate Program, University of Iowa, Iowa City, Iowa.;Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.;Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Medical Scientist Training Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [20] Molecular Medicine Graduate Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Cancer Biology Graduate Program, University of Iowa, Iowa City, Iowa.;Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa.;Medical Scientist Training Program, Carver College of Medicine, University of Iowa, Iowa City, Iowa.;Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa. [21]
DOI 10.1158/1078-0432.CCR-23-0749
PMID 37410426
发布时间 2024-05-23
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Clinical cancer research : an official journal of the American Association for Cancer Research

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