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A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2.

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第一作者: Marta,Losa
第一单位: Program in Craniofacial Biology, Institute for Human Genetics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Department of Orofacial Sciences and Department of Anatomy, University of California San Francisco, San Francisco, CA, USA.
作者单位: Program in Craniofacial Biology, Institute for Human Genetics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Department of Orofacial Sciences and Department of Anatomy, University of California San Francisco, San Francisco, CA, USA. [1] Center for Cancer Research, Medical University of Vienna, Vienna, Austria. [2] Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.;Department for Biomedical Research (DBMR), University of Bern, Bern, Switzerland.;Department of Cardiology, Bern University Hospital, Bern, Switzerland. [3] Developmental Genetics, Department Biomedicine, University of Basel, Basel, Switzerland. [4] School of Medical Sciences, University of Manchester, Manchester, UK. [5] Cancer and Developmental Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA. [6] Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA.;Broad Institute of MIT and Harvard, Cambridge, MA, USA. [7] Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. [8] Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.;US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.;School of Natural Sciences, University of California, Merced, Merced, CA, 95343, USA. [9] Program in Craniofacial Biology, Institute for Human Genetics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Department of Orofacial Sciences and Department of Anatomy, University of California San Francisco, San Francisco, CA, USA. licia.selleri@ucsf.edu. [10]
DOI 10.1038/s41467-023-39443-z
PMID 37414772
发布时间 2023-11-18
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