A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma.

导出 OA

翻译打印收藏纠错

作者： Vincent,Gureghian ^[1] ; Hailee,Herbst ^[1] ; Ines,Kozar ^[2] ; Katarina,Mihajlovic ^[3] ; Noël,Malod-Dognin ^[3] ; Gaia,Ceddia ^[3] ; Cristian,Angeli ^[1] ; Christiane,Margue ^[1] ; Tijana,Randic ^[1] ; Demetra,Philippidou ^[1] ; Milène Tetsi,Nomigni ^[1] ; Ahmed,Hemedan ^[4] ; Leon-Charles,Tranchevent ^[4] ; Joseph,Longworth ^[5] ; Mark,Bauer ^[1] ; Apurva,Badkas ^[1] ; Anthoula,Gaigneaux ^[1] ; Arnaud,Muller ^[6] ; Marek,Ostaszewski ^[4] ; Fabrice,Tolle ^[1] ; Nataša,Pržulj ^[3] ; Stephanie,Kreis ^[7]

作者单位： Department of Life Sciences and Medicine, University of Luxembourg, 6, Avenue du Swing, L-4367, Belvaux, Luxembourg. ^[1] Laboratoire National de Santé, Dudelange, Luxembourg. ^[2] Barcelona Supercomputing Center, 08034, Barcelona, Spain. ^[3] Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg. ^[4] Experimental and Molecular Immunology, Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg. ^[5] LuxGen, TMOH and Bioinformatics platform, Data Integration and Analysis unit, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg. ^[6] Department of Computer Science, University College London, London, WC1E 6BT, UK. ^[7] ICREA, Pg. Lluís Companys 23, 08010, Barcelona, Spain. ^[8] Department of Life Sciences and Medicine, University of Luxembourg, 6, Avenue du Swing, L-4367, Belvaux, Luxembourg. stephanie.kreis@uni.lu. ^[9]

主题词人类(Humans);细胞系, 肿瘤(Cell Line, Tumor);黑色素瘤(Melanoma);蛋白激酶抑制剂(Protein Kinase Inhibitors);膜蛋白质类(Membrane Proteins);GTP磷酸水解酶类(GTP Phosphohydrolases)

DOI 10.1038/s41417-023-00640-z

PMID 37420093

发布时间 2023-11-06

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交