Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase.

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作者： Lenka,Koudelková ^[1] ; Markéta,Pelantová ^[2] ; Zuzana,Brůhová ^[1] ; Martin,Sztacho ^[1] ; Vojtěch,Pavlík ^[1] ; Dalibor,Pánek ^[1] ; Jakub,Gemperle ^[3] ; Pavel,Talacko ^[1] ; Jan,Brábek ^[4] ; Daniel,Rösel ^[1]

作者单位： Department of Cell Biology, BIOCEV, Faculty of Science, Charles University, Vestec, Czech Republic. ^[1] Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic. ^[2] Imaging Methods Core Facility at BIOCEV, Faculty of Science, Charles University, Vestec, Czech Republic. ^[3] Proteomics Core Facility at BIOCEV, Faculty of Science, Charles University, Vestec, Czech Republic. ^[4]

关键词 SH3 domain Src biochemistry cell biology cell transformation chemical biology invasiveness mouse phosphorylation protein structure

主题词 src族激酶类(src-Family Kinases);磷酰化(Phosphorylation);src同源域(src Homology Domains);酪氨酸(Tyrosine);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases)

DOI 10.7554/eLife.82428

PMID 37428018

发布时间 2023-07-31

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