Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease.

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作者： Yasuteru,Inoue ^[1] ; Francis,Shue ^[1] ; Guojun,Bu ^[2] ; Takahisa,Kanekiyo ^[3]

作者单位： Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. ^[1] SciNeuro Pharmaceuticals, Rockville, MD, 20850, USA. ^[2] Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. kanekiyo.takahisa@mayo.edu. ^[3]

关键词 Arteriolosclerosis Blood–brain barriers (BBB)Cerebral amyloid angiopathy (CAA)Cerebral small vessel disease (cSVD)Glymphatic drainage Hypoperfusion/Hypoxia Intramural periarterial drainage (IPAD)Vascular cognitive impairment and dementia (VCID)Vascular inflammation

主题词人类(Humans);痴呆, 血管性(Dementia, Vascular);阿尔茨海默病(Alzheimer Disease);因果律(Causality);危险因素(Risk Factors)

DOI 10.1186/s13024-023-00640-5

PMID 37434208

发布时间 2024-11-16

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