首页> EMBO reports> MOV10 recruits DCP2 to decap human LINE-1 RNA by forming large cytoplasmic granules with phase separation properties.

MOV10 recruits DCP2 to decap human LINE-1 RNA by forming large cytoplasmic granules with phase separation properties.

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第一作者： Qian,Liu

第一单位： Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical School, Beijing, China.

作者： Qian,Liu ^[1] ; Dongrong,Yi ^[1] ; Jiwei,Ding ^[1] ; Yang,Mao ^[1] ; Shujie,Wang ^[1] ; Ling,Ma ^[1] ; Quanjie,Li ^[1] ; Jing,Wang ^[1] ; Yongxin,Zhang ^[1] ; Jianyuan,Zhao ^[1] ; Saisai,Guo ^[1] ; Zhenlong,Liu ^[2] ; Fei,Guo ^[3] ; Dongbing,Zhao ^[4] ; Chen,Liang ^[2] ; Xiaoyu,Li ^[1] ; Xiaozhong,Peng ^[5] ; Shan,Cen ^[1]

作者单位： Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical School, Beijing, China. ^[1] Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, QC, Canada. ^[2] Institute of Pathogen Biology, Chinese Academy of Medical Science, Beijing, China. ^[3] National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical School, Beijing, China. ^[4] State Key Laboratory of Medical Molecular Biology, Department of Molecular Biology and Biochemistry, Institute of Basic Medical Sciences, Medical Primate Research Center, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, China. ^[5]

关键词 DCP2 LINE-1 MOV10 RNA decap liquid-liquid phase separation

医学主题词人类(Humans);细胞质颗粒(Cytoplasmic Granules);内切核糖核酸酶类(Endoribonucleases);长核苷酸元件(Long Interspersed Nucleotide Elements);RNA(RNA);RNA解螺旋酶类(RNA Helicases)

DOI 10.15252/embr.202256512

PMID 37437058

发布时间 2024-09-24

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