首页> Veterinary research> Dihydromyricetin inhibits African swine fever virus replication by downregulating toll-like receptor 4-dependent pyroptosis in vitro.

Dihydromyricetin inhibits African swine fever virus replication by downregulating toll-like receptor 4-dependent pyroptosis in vitro.

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第一作者： Yang,Chen

第一单位： Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.;African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, China.;Research Center for African Swine Fever Prevention and Control, South China Agricultural University, Guangzhou, China.

作者： Yang,Chen ^[1] ; Zebu,Song ^[2] ; Hao,Chang ^[1] ; Yanchen,Guo ^[3] ; Zhi,Wei ^[1] ; Yankuo,Sun ^[4] ; Lang,Gong ^[5] ; Zezhong,Zheng ^[6] ; Guihong,Zhang ^[7]

作者单位： Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.;African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, China.;Research Center for African Swine Fever Prevention and Control, South China Agricultural University, Guangzhou, China. ^[1] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.;African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, China.;Maoming Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming, Guangdong, China. ^[2] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.;African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, China.;Key Laboratory of Animal Vaccine Development, Ministry of Agriculture and Rural Affairs, Guangzhou, China. ^[3] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.;African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, China.;Maoming Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming, Guangdong, China.;Key Laboratory of Animal Vaccine Development, Ministry of Agriculture and Rural Affairs, Guangzhou, China. ^[4] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.;African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, China.;Research Center for African Swine Fever Prevention and Control, South China Agricultural University, Guangzhou, China.;Maoming Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming, Guangdong, China. ^[5] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China. zezhong@scau.edu.cn.;African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, China. zezhong@scau.edu.cn.;Maoming Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming, Guangdong, China. zezhong@scau.edu.cn. ^[6] Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China. guihongzh@scau.edu.cn.;African Swine Fever Regional Laboratory of China (Guangzhou), Guangzhou, China. guihongzh@scau.edu.cn.;Research Center for African Swine Fever Prevention and Control, South China Agricultural University, Guangzhou, China. guihongzh@scau.edu.cn.;Maoming Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming, Guangdong, China. guihongzh@scau.edu.cn.;Key Laboratory of Animal Vaccine Development, Ministry of Agriculture and Rural Affairs, Guangzhou, China. guihongzh@scau.edu.cn.;National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, China. guihongzh@scau.edu.cn. ^[7]

关键词 African swine fever virus TLR4/MyD88/MAPK/NF-κB signaling dihydromyricetin pyroptosis

医学主题词动物(Animals);猪(Swine);非洲猪瘟病毒(African Swine Fever Virus);Toll样受体4(Toll-Like Receptor 4);非洲猪瘟(African Swine Fever);抗病毒药(Antiviral Agents);猪疾病(Swine Diseases)

DOI 10.1186/s13567-023-01184-8

PMID 37438783

发布时间 2023-07-18

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