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首页> International journal of molecular sciences> Analysis of the Mutational Landscape of Osteosarcomas Identifies Genes Related to Metastasis and Prognosis and Disrupted Biological Pathways of Immune Response and Bone Development.

Analysis of the Mutational Landscape of Osteosarcomas Identifies Genes Related to Metastasis and Prognosis and Disrupted Biological Pathways of Immune Response and Bone Development.

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作者： Sara Ferreira,Pires ^[1] ; Juliana Sobral de,Barros ^[1] ; Silvia Souza da,Costa ^[1] ; Gabriel Bandeira do,Carmo ^[1] ; Marília de Oliveira,Scliar ^[1] ; André van Helvoort,Lengert ^[2] ; Érica,Boldrini ^[3] ; Sandra Regini Morini da,Silva ^[4] ; Daniel Onofre,Vidal ^[2] ; Mariana,Maschietto ^[5] ; Ana Cristina Victorino,Krepischi ^[1]

作者单位： Human Genome and Stem-Cell Research Center, Institute of Biosciences, Department of Genetics and Evolutionary Biology, University of São Paulo, São Paulo 05508-090, Brazil. ^[1] Molecular Oncology Research Center (CPOM), Barretos Cancer Hospital, Barretos 14784-384, Brazil. ^[2] Barretos Children's Cancer Hospital, Barretos 14784-400, Brazil. ^[3] Department of Pathology, Barretos Cancer Hospital, Barretos 14784-400, Brazil. ^[4] Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas 13083-884, Brazil. ^[5]

关键词 DMD KNL1 PTPRQ RB1 TNFRSF11B TP53 ZFHX4 chromoanasynthesis chromothripsis osteosarcoma

主题词人类(Humans);突变(Mutation);DNA拷贝数变异(DNA Copy Number Variations);基因组不稳定性(Genomic Instability);骨肉瘤(Osteosarcoma);骨肿瘤(Bone Neoplasms);骨发育(Bone Development);免疫(Immunity);受体样蛋白质酪氨酸磷酸酶类, 3类(Receptor-Like Protein Tyrosine Phosphatases, Class 3)

DOI 10.3390/ijms241310463

PMID 37445641

发布时间 2023-07-18

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International journal of molecular sciences

International journal of molecular sciences

2023年24卷13期

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